Depressive disorder
Conditions
Interventions
A Group (Real HI-tACS combined with Real iTBS treatment group):Real HI-tACS combined with Real iTBS treatment
B Group (Sham HI-tACS combined with Real iTBS treatment group):Sham HI-tACS combined with Real iTBS treatment
C Group (Real HI-tACS combined with Sham iTBS treatment group):Real HI-tACS combined with Sham iTBS treatment
Sponsors
Ningbo First Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Age 18-65 years old, right-handed; 2. Meets the diagnostic criteria for depression in the Diagnostic and Statistical Manual of Mental Disorders -5; HAMD-17 scores >= 17; 3. Agree to participate in this study and sign the informed consent form; 4. The subjects have been consistently taking the same type and dose of antidepressant medication for at least 15 days prior to enrollment;
Exclusion criteria
Exclusion criteria: 1. Serious physical illness; 2. Current or past organic brain or neurological disorders; 3. According to the Mini-International Neuropsychiatric Interview(M.I.N.I.)comorbidities with other mental illnesses are evaluated; 4. Previous or current history of receiving rTMS, transcranial electrical stimulation, electroconvulsive therapy, or other neuroregulatory treatments; 5. There are contraindications for transcranial magnetic stimulation therapy, such as personal or family history of epilepsy, cochlear implants, increased intracranial pressure, pacemaker implantation, or head metal implants; 6. Pregnancy or lactation; 7. Participate in concurrent clinical trials;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Efficacy rate after 2 weeks of treatment;Remission rate after 2 weeks of treatment; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hamilton Depression Rating Scale-17;Hamilton Anxiety Rating Scale;Pittsburgh Sleep Quality Index;Schedule for Affective Disorders and Schizophrenia - Life Events Schedule;Brief Symptom Inventory; | — |
Countries
China
Contacts
Public ContactJi Yunxin
Ningbo First Hospital
Outcome results
None listed