Gastroesophageal reflux disease (GERD), esophagitis, and management of acid-related heartburn symptoms
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Meet the diagnostic criteria for GERD; 2.Have endoscopically confirmed Los Angeles grade B or C esophagitis; 3.Are scheduled to undergo elective endoscopic treatment with PECC, ARMS, or MUSE-TIF; 4.Have provided informed consent; 5. Age 18-75
Exclusion criteria
Exclusion criteria: 1.Los Angeles grade D esophagitis or Barrett’s esophagus (long-segment, >3 cm); 2.Esophageal stricture or tumor; 3.Hiatal hernia >3 cm; 4.Severe cardiac, pulmonary, hepatic, or renal insufficiency; 5.History of upper gastrointestinal surgery; 6.Pregnant or lactating women;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Medication use;Overall treatment success rate 6 months after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| The extent of improvement in GERD symptoms;Quality of life; | — |
Countries
China
Contacts
Shanghai General Hospital