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The Role and Mechanism of Type I Collagen Homotrimer in Microvascular Invasion of Hepatocellular Carcinoma

The Role and Mechanism of Type I Collagen Homotrimer in Microvascular Invasion of Hepatocellular Carcinoma

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600119996
Enrollment
Unknown
Registered
2026-03-06
Start date
2026-03-20
Completion date
Unknown
Last updated
2026-03-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hepatocellular carcinoma

Interventions

MVI positive group:None
MVI negtive group:None

Sponsors

Ningbo Medical Centre Lihuili Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Preoperative imaging revealed no evidence of distant metastasis; 2. Underwent curative-intent hepatectomy for HCC; 3. The hepatic resection specimen was pathologically confirmed as hepatocellular carcinoma (HCC); 4. Received no other antitumor therapy prior to surgery; 5. Had complete clinical and pathological data available for analysis.

Exclusion criteria

Exclusion criteria: 1. Received preoperative antimicrobial treatment. 2. Exhibited macroscopic vascular invasion as determined by postoperative pathology. 3. Had a history of other malignant tumors; 4. Classified as Child-Pugh class C liver function. 5. Suffered from inflammatory diseases or severe infections.

Design outcomes

Primary

MeasureTime frame
recurrence time;Expression level of type I collagen homotrimer;Disease free survival;—

Countries

China

Contacts

Public ContactWang Ke

Ningbo Medical Centre Lihuili Hospital

13867851869@163.com+86 574 55836149

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 14, 2026