None
Conditions
Interventions
Non-tegileridine group:None
Sponsors
The Second Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients undergoing elective non-cardiac surgery under general anesthesia; 2. Age 18-65 years old, BMI 18-28 kg/^2; 3. American Society of Anesthesiologists (ASA) grade I-III; 4. Accept PCIA voluntarily and can understand and sign the informed consent;
Exclusion criteria
Exclusion criteria: 1. Patients with previous neurological diseases (such as depression, epilepsy, etc.); 2. Patients with severe liver and kidney dysfunction; 3. Patients allergic to tegileridine; 4. Those with hearing, intelligence, communication, cognitive impairment, and pregnant and lactating women; 5. Unable to cooperate with the study for any reason or considered not suitable for inclusion in the trial by the investigators;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of moderate and severe pain within 24 hours after surgery with NRS>=4; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sleep Satisfaction Score;Postoperative safety indicators;The occurrence of chronic pain in patients at 3 months after operation was recorded; | — |
Countries
China
Contacts
Public ContactHuang He
The Second Affiliated Hospital of Chongqing Medical University
Outcome results
None listed