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Study on the early predictive value of soluble growth stimulating expressed gene 2 protein and Endothelin-1 for the severity of hypertensive disorder complicating pregnancy

Study on the early predictive value of soluble growth stimulating expressed gene 2 protein and Endothelin-1 for the severity of hypertensive disorder complicating pregnancy

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600119989
Enrollment
Unknown
Registered
2026-03-06
Start date
2026-04-01
Completion date
Unknown
Last updated
2026-03-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hypertensive disorders of pregnancy

Interventions

Sponsors

Huaibei Maternal and Child Health Care Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. Diagnosis of hypertensive disorder complicating pregnancy according to the latest guideline diagnostic criteria; 2. Mental Normal, can carry on the normal communication pregnant woman; 3. Pregnant women and their families gave informed consent to the study; 4. Pregnancy formal pregnancy examination, and can complete the pregnancy examination data collection; 5. No previous history of hypertension, diabetes and other basic diseases; 6. No history of other serious illness.

Exclusion criteria

Exclusion criteria: 1. Mental disorders, unable to communicate properly with pregnant women; 2. Combined with severe congenital diseases or underlying diseases that may affect the condition of hypertensive disorder complicating pregnancy; 3. Pregnancy test is not regular, and pregnancy test data is not complete; 4. The pregnant women who didn't give birth in our hospital.

Design outcomes

Primary

MeasureTime frame
Soluble growth stimulating expression gene 2 protein;Endothelin-1;ROC curve;Area Under the ROC Curve;

Countries

China

Contacts

Public ContactWang Zihong

Huaibei Maternal and Child Health Care Hospital

ahmu@sina.cn+86 561 302 3157

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 14, 2026