osteoarthritis, OA
Conditions
Interventions
Observation group:None
Sponsors
Southern Medical University Southern Hospital
Eligibility
Sex/Gender
All
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Prospective cohort studies section: (1).The subjects voluntarily participated and signed the informed consent form under the premise of informed consent; (2).50 = grade II; Pain visual analogue scale (VAS) >= 3. 2.Retrospective cohort studies section: (1) Patients whose visit period was from October 2010 to September 2024 (and who would not return to the hospital for further treatment at a later stage) were exempted from informed consent; (2). Patients whose visit period was from October 2024 to September 2025 were required to sign an informed consent form; (3).50 = grade II; Pain visual analogue scale (VAS) >= 3.
Exclusion criteria
Exclusion criteria: 1.Moderate to severe heart failure (New York Heart Association grade 3-4); 2.All subjects had developed gastrointestinal disease within 8 weeks before sampling and had taken antibiotics or probiotics or prebiotics that can affect the intestinal flora; 3.Severe deformity of lower limb joints, pain and other disorders affecting normal walking; 4.Have undergone surgery or arthroscopic treatment. 5.Patients with severe visceral lesions, other severe metabolic disorders and bone tumors; 6.Those who had received immunosuppressant, adrenocortical hormone or systemic therapy in the previous 3 weeks; 7.Mentally Ill, intellectually disabled, pregnant and lactating women; 8.In the judgment of the researchers, it was not appropriate to participate in this study;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Provide a public archive of data and images from cohort studies; | — |
Secondary
| Measure | Time frame |
|---|---|
| Lequesne Algofunctional Index;36-item Short-Form,SF-36;Kellgren-Lawrence grading scale?;Range of motion;Osteoarthritis Quality of Life Scale,OAQoL;Western Ontario and McMaster Universities Osteoarthritis Index;Visual Analogue Scale;Indicators of streptococcal infection;Osteoarthritis Research Society International Score?;Knee Society Score, KSS;Circumference of limb swelling;Swollen Joint Count, Tender Joint Count; | — |
Countries
China
Contacts
Public ContactJun Xiao
Southern Medical University Southern Hospital
Outcome results
None listed