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Constructing an interpretable machine learning prognostic model for patients with Takotsubo syndrome based on CMR multimodal quantitative parameters

Constructing an interpretable machine learning prognostic model for patients with Takotsubo syndrome based on CMR multimodal quantitative parameters

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600119987
Enrollment
Unknown
Registered
2026-03-06
Start date
2026-04-01
Completion date
Unknown
Last updated
2026-03-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Takotsubo syndrome (TTS)

Interventions

TTS Patient Cohort:None

Sponsors

Lishui Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.Transient left ventricular dysfunction characterized by apical ballooning or mid-ventricular, basal, or focal wall motion abnormalities, potentially involving the right ventricle; 2.Localized wall motion abnormalities typically extend beyond the distribution of a single epicardial vessel; 3.Emotional, physical, or combined triggering factors may precede TTS onset (non-essential); 4.Neurological disorders and pheochromocytoma may serve as precipitating factors for TTS; 5.New-onset ECG abnormalities: Moderate elevation of cardiac biomarkers (troponin and creatine kinase) in most cases; marked elevation of brain natriuretic peptide (BNP); 6.Severe coronary artery disease (CAD) is not incompatible with TTS;

Exclusion criteria

Exclusion criteria: 1.Combination of other cardiac diseases confirmed by CMR such as hypertrophic cardiomyopathy, cardiac nodular disease, arrhythmogenic right ventricular cardiomyopathy, etc. 2.Age less than 18 years old; 3.Interruption of follow-up in the middle of the follow-up or loss of follow-up; 4.Patients with incomplete images or image artifacts affecting post-processing; 5. Patients with renal insufficiency.

Design outcomes

Primary

MeasureTime frame
Adverse Cardiovascular Events;Multimodal Quantitative CMR Parameters;

Countries

China

Contacts

Public ContactLu Chenying

Lishui Central Hospital

luchenying@zju.edu.cn+86 678 2129120

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 14, 2026