Hyperlipidemia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.It meets the diagnostic criteria in the "Chinese Guidelines for the Prevention and Treatment of Dyslipidemia in Adults (Revised Edition 2016)", with LDL-C being >= 130 mg/dl; 2. During the three months prior to the study, no lipid-lowering drugs, probiotics, antibiotics, or other medications were used; 3. The patient's clinical case data is complete; 4. All patients are required to receive statin therapy, and they have no allergic reaction to statins.
Exclusion criteria
Exclusion criteria: 1.Combine digestive system diseases, diabetes and other diseases that may affect the intestinal flora; 2. Merge liver and kidney function abnormalities; 3. Merge with severe cognitive impairment or mental-related disorders; 4. Patients with malignant tumors are combined.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fecal microbiota; | — |
Secondary
| Measure | Time frame |
|---|---|
| Metabolic indicators: glycated hemoglobin (HbA1c), fasting blood glucose, OGTT-2h blood glucose, lipid profile.; | — |
Countries
China
Contacts
The Second Affiliated Hospital of the Army Medical University