Pudendal neuralgia
Conditions
Interventions
Pudendal nerve pulsed radiofrequency group (PRF group):Pudendal nerve pulsed radiofrequency
Pudendal nerve electrical stimulation group (PNS group):Pudendal nerve electrical stimulation
Sponsors
Peking University People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age between 18 and 80 years; 2. Diagnosis of pudendal neuralgia meets the Nantes criteria, with the main criteria including: (1) Pain located in the distribution area of the pudendal nerve; (2) Pain worsens when sitting; (3) Pain does not wake the patient at night; (4) No associated sensory loss; (5) Pudendal nerve diagnostic block is effective (pain relief >=50%); 3. Conservative treatment for more than 3 months (e.g., pelvic floor rehabilitation, oral medications such as gabapentin, pregabalin, duloxetine, fluphenazine, clonazepam, etc.; pudendal nerve injection therapy, etc.) and poor response to conservative treatment or intolerance to drug side effects; 4. Ability to sign an informed consent form;
Exclusion criteria
Exclusion criteria: 1.Pain attributable to pelvic malignancy or autoimmune disease; 2.Pain resulting from prior pelvic surgery; 3.Current anticoagulant therapy or coagulation disorder; 4.Pregnancy; 5.Local or systemic infection; 6.Poorly controlled diabetes mellitus; 7.Inability to complete questionnaire assessments;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain relief response rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Overall surgical satisfaction;Pudendal neurophysiology: bulbocavernosus reflex and pudendal somatosensory evoked potentials;Factors influencing surgical outcomes;Analgesic usage;Neuroinflammation;Complications; | — |
Countries
China
Contacts
Public ContactLiu Yiming
Peking University People's Hospital
Outcome results
None listed