none
Conditions
Interventions
Trial group:None
Sponsors
The Second Xiangya Hospital, Central South University
Eligibility
Sex/Gender
All
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: 1. Age 18-64 years; 2. ASA physical status I–II; 3. BMI 18–28 kg/m²; 4. Scheduled to undergo surgery under general anesthesia with laryngeal mask airway insertion.
Exclusion criteria
Exclusion criteria: 1. Allergy to benzodiazepines; 2. Difficult airway as assessed by the anesthesiologist; 3. Previously diagnosed coronary heart disease or other cardiopulmonary insufficiency; 4. Confirmed psychiatric or neurological disorders, such as depression, anxiety, schizophrenia, or epilepsy; 5. Use of medications that may affect EEG activity, including sedative-hypnotics and/or antiepileptic drugs, within 24–48 h before surgery; 6. Abnormal liver or kidney function on laboratory testing, including total bilirubin >=3.0 mg/dL, or aspartate aminotransferase (AST) >=2.5 × the upper limit of normal, or alanine aminotransferase (ALT) =2.5 × the upper limit of normal, or renal disease (serum creatinine >=2 mg/dL); 7. Difficulty with electrode placement or persistently inadequate EEG signal quality; 8. Refusal to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Delta-band spectral power;vital signs; | — |
Secondary
| Measure | Time frame |
|---|---|
| Alpha-band spectral power;Alpha-band coherence;PSI values at different time points; | — |
Countries
Chian
Contacts
Public ContactHaiding Zou
The Second Xiangya Hospital, Central South University
Outcome results
None listed