None
Conditions
Interventions
Cardiovascular Observation Group:None
Sponsors
Shanghai Children's Hospital
Eligibility
Sex/Gender
All
Age
6 Years to 17 Years
Inclusion criteria
Inclusion criteria: 1. Age: 6 - 17 years old (inclusive of the boundaries). 2. Chinese nationality, both parents being of Han ethnicity in China. 3. Judged to be healthy based on medical history, physical examination and basic laboratory tests (if there are archived records). 4. Resting sitting blood pressure is lower than the 90th percentile of blood pressure for children of the same age, gender and height. 5. Body Mass Index (BMI) is between the 5th and 85th percentiles for the same age and gender. 6. The legal guardian signs the informed consent form, and the subject (>= 8 years old) signs the informed consent.
Exclusion criteria
Exclusion criteria: 1. Known to have any cardiovascular disease (including congenital heart disease, cardiomyopathy, post-Kawasaki disease sequelae, arrhythmia, etc.). 2. Known to have any chronic disease that may affect the cardiovascular system (such as chronic kidney disease, autoimmune diseases, endocrine diseases such as diabetes, thyroid dysfunction, etc.). 3. Had a recent (within 3 months) history of acute infection or hospitalization. 4. Have been taking any medications that may affect cardiovascular function or blood pressure (such as psychotropic drugs, hormones, etc.). 5. Detected heart murmur (>=2/6 grade) or other significant abnormal signs during physical examination. 6. Any cardiac structural or functional abnormalities (such as moderate or above valve regurgitation, pericardial effusion, ventricular hypertrophy, systolic dysfunction, etc.) were found during echocardiography examination.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Arterial wave velocity index;Overall longitudinal strain of the left ventricle;Cardiovascular coupling ratio; | — |
Secondary
| Measure | Time frame |
|---|---|
| Technical performance indicators;Hemodynamic indicators;Demographics and physical indicators; | — |
Countries
China
Contacts
Public ContactZhaojun Li
Shanghai Children's Hospital
Outcome results
None listed