Post-stroke motor aphasia
Conditions
Interventions
Treatment group:Conventional speech and language therapy was combined with tDCS targeting the left dorsolateral prefrontal cortex.
Control group:Conventional speech and language therapy was combined with sham tDCS targeting the left dorsolateral prefrontal cortex.
Healthy control group:Only scale-based assessments and fNIRS measurements were performed, and no intervention was administered.
Sponsors
The Second People's Hospital of Lishui
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: All participants were patients with post-stroke motor aphasia (PSMA) recruited from the outpatient and inpatient departments of our hospital. 1.Stroke was diagnosed according to the Chinese Cerebrovascular Disease Classification (2015) and was confirmed by MRI or CT as a left-hemispheric stroke; the aphasia type was identified as motor aphasia using the Chinese Standard Aphasia Examination developed by the China Rehabilitation Research Center. 2.Eligibility criteria were as follows: a Boston Diagnostic Aphasia Examination (BDAE) severity rating of >=1; 3.aphasia duration of >=4 months; 4. Age 18–75 years; 5. Premorbid native language of Mandarin Chinese; 6. Premorbid right-handedness as assessed by the Edinburgh Handedness Inventory; 7. Ability to cooperate with speech and language rehabilitation with good adherence; 8. And the capacity to understand and agree to the treatment plan and to provide written informed consent.
Exclusion criteria
Exclusion criteria: 1.Participants with severe untreated psychiatric disorders; 2.PSMA attributable to neurodegenerative disease or traumatic brain injury; 3.Any contraindications to transcranial direct current stimulation (tDCS) or functional near-infrared spectroscopy (fNIRS); 4.Inability to complete the required assessments and rehabilitation procedures according to the study protocol were not eligible for inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Speech function; | — |
Secondary
| Measure | Time frame |
|---|---|
| Aphasia severity;Ability to communicate in daily life;Quality of life;Cortical plasticity.; | — |
Countries
China
Contacts
Public ContactMa Kaimin
The Second People's Hospital of Lishui
Outcome results
None listed