Acute myocardial infarction
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Group A (High-Risk Population) (1) Age >= 18 years; (2) Clinically diagnosed with stable angina or unstable angina; (3) Voluntarily participates in this study and signs the informed consent form; (4) Able to cooperate with baseline surveys, biological sample collection, and long-term follow-up. 2. Group B (Diagnosed Myocardial Infarction Population) (1) Age >= 18 years; (2) Meets the diagnostic criteria of the "Fourth Universal Definition of Myocardial Infarction"; (3) Time from onset to admission <= 24 hours (priority given to emergency PCI patients); (4) Voluntarily participates in this study and signs the informed consent form; (5) Able to cooperate with baseline surveys, biological sample collection, and long-term follow-up.
Exclusion criteria
Exclusion criteria: 1. Patients with terminal malignant tumors, expected survival < 1 year; 2. Patients with severe liver or kidney dysfunction (eGFR < 30 mL/min/1.73m^2, or Child-Pugh Class C); 3. Patients with active autoimmune diseases or long-term use of immunosuppressants; 4. Pregnant or breastfeeding women; 5. Inability to complete informed consent or severe cognitive impairment; 6. Previous participation in other clinical trials that may have intervention conflicts with this study; 7. Other conditions deemed unsuitable for inclusion by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| all-cause mortality; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cardiovascular death (including fatal MI, death from worsening heart failure, sudden cardiac death, stroke death, cardiovascular surgery-related death);Recurrent Myocardial Infarction (Fourth Edition UDMI);Readmission due to heart failure (requiring intravenous anti-heart failure treatment and hospitalization >=24 hours);Target vessel/non-target vessel revascularization;Stroke (imaging confirmed ischemic or hemorrhagic);Definite or probable stent thrombosis (ARC);Severe bleeding (BARC 3 or 5); | — |
Countries
China
Contacts
Fuzhou University Affiliated Provincial Hospital