Women with gestational diabetes mellitus, aged 18-40 with a singleton pregnancy.
Conditions
Interventions
NE group:using norepinephrine infusion to prevent hypotension
Sponsors
Women’s Hospital, Zhejiang University School of Medicine
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1.Pregnant women with gestational diabetes mellitus (aged 18–40 years, singleton pregnancy) scheduled for elective cesarean delivery.
Exclusion criteria
Exclusion criteria: 1.Contraindications to neuraxial anesthesia; 2.Active labor; 3.Placenta previa or other placental abnormalities; 4.History of or pregnancy-induced hypertension, known cardiovascular or cerebrovascular disease; 5.Body weight 100 kg, height 180 cm; 6.Inability or refusal to provide informed consent; 7.Allergy to norepinephrine; 8.Other conditions deemed unsuitable for participation by the investigators (e.g., psychiatric disorders, inability to clearly communicate adverse drug reactions, etc.);
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| hypotension;Success rate of maintaining mean arterial pressure (MAP) >= 80% of baseline after subarachnoid anesthesia with a specified dose of norepinephrine infusion; | — |
Secondary
| Measure | Time frame |
|---|---|
| The incidence of bradycardia, tachycardia, hypertension, and nausea and vomiting; | — |
Countries
China
Contacts
Public ContactLihong Sun
Women’s Hospital, Zhejiang University School of Medicine
Outcome results
None listed