sarcopenia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Meets the diagnostic criteria for severe AS by transthoracic echocardiography: aortic valve blood flow velocity greater than 4 m/s, or mean transvalvular pressure gradient of the aortic valve >=40 mmHg (1 mmHg = 0.133 kPa), or valve orifice area 70 mm; Left ventricular end-systolic diameter > 50 mm; Left ventricular end-systolic diameter index > 25 mm/m2; LVEF <=55%.
Exclusion criteria
Exclusion criteria: 1. Acute myocardial infarction occurred within the last 30 days; 2. Infective endocarditis or intracardiac thrombosis; 3. Acute heart failure not corrected; 4. Left ventricular outflow tract obstruction; 5. Complicated with malignant tumor, with an expected lifespan of less than 1 year.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| All-cause mortality and other long-term adverse cardiovascular events;perioperative complications; | — |
Countries
China
Contacts
Ningbo Medical Centre Lihuili Hospital