postoperative sleep disoder
Conditions
Interventions
Propofol group:Propofol?induced and maintained surgical anesthesia
Cypofol group:Cypofol-induced and maintained surgical anesthesia
Sponsors
Women’s Hospital, Zhejiang University School of Medicine
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Age 18-65 years old; 2. ASA Level I-II; 3. Patients undergoing gynecological laparoscopic surgery; 4. Grow more than 1 hour during surgery; 5. This study must be approved by the ethics committee of the hospital, and all participating patients must sign the anesthesia and trial informed consent form.
Exclusion criteria
Exclusion criteria: 1. The patient refuses to participate in the study; 2. Body mass index (BMI) below 18 or above 30; 3. A clear history of psychiatric or sleep disorders (depression, schizophrenia, sleep disorders with PSQI >7, perimenopausal syndrome, etc.) or a family history of sleep problems in second- or third-degree relatives; 4. Cognitive impairment or communication difficulties; recent history of drug abuse or recent use of central nervous system-acting drugs including sedatives or psychoactive stimulants; 5. Contraindications or allergy to remimazolam or propofol.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of Postoperative Sleep Disturbances; | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of Recovery;Pittsburgh Sleep Quality Index, PSQI;Burst-Suppression Ratio(BSR);Three - Dimensional Confusion Assessment Method(3D - CAM );EEG Delta wave;Postoperative Adverse Reactions and Their Incidence Rates;Self-Rating Anxiety Scale(SAS);Peak Frequency of Alpha-Beta Waves;EEG Alpha wave;Insomnia Severity Index Score(ISI);Electroencephalograph(EEG) Beta Waves;NRS for Sleep;Electromyographic Index(EMG);depth of anesthesia index(AI);Electroencephalograph(EEG) Beta Waves;Postoperative Hospitalization Time;EEG Theta wave;EEG Gamma wave;NRS for pain;Ramsay Sedation Scale;Incidence of Postoperative Sleep Disturbance;Alpha-Beta Wave Peak Power; | — |
Countries
China
Contacts
Public ContactLili Xu
Women’s Hospital, Zhejiang University School of Medicine
Outcome results
None listed