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Clinicopathological and Genetic Mutations of Papillary Thyroid Carcinoma

Exploring Genetic Variants of Some Genes with Related Thyroid Cancer

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600119910
Enrollment
Unknown
Registered
2026-03-05
Start date
2024-12-01
Completion date
Unknown
Last updated
2026-03-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thyroid Cancer

Interventions

Observation group:None

Sponsors

Sulaimani university
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients were eligible for inclusion if they had a histopathologically confirmed diagnosis of PTC, underwent total thyroidectomy during the study period, and had available formalin-fixed, paraffin-embedded (FFPE) tumor tissue suitable for molecular analysis. Only cases with complete clinicopathological data, including demographic, biochemical, and tumor-related parameters, were enrolled.

Exclusion criteria

Exclusion criteria: Patients were excluded if they had any other histological type of thyroid cancer, presented with distant metastasis at the time of diagnosis, or had insufficient or poor-quality FFPE samples that failed DNA extraction or sequencing quality control. Individuals with recurrent thyroid cancer, previous thyroid surgery, radiotherapy, or systemic therapy were also excluded, as well as cases with incomplete medical records that could not be used for statistical evaluation.

Design outcomes

Primary

MeasureTime frame
Prevalence of BRAF mutation;

Countries

IRAQ

Contacts

Public ContactRawezh Qadir M Salih

Sulaimani university

rawezh.mohammed@univsul.edu.iq+964 750 109 7039

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 14, 2026