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A multicenter randomized controlled trial (RCT) on the effect of ropivacaine at different temperatures for subarachnoid anesthesia on urinary retention after arthroscopic knee surgery

A multicenter randomized controlled trial (RCT) on the effect of ropivacaine at different temperatures for subarachnoid anesthesia on urinary retention after arthroscopic knee surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600119909
Enrollment
Unknown
Registered
2026-03-05
Start date
2026-03-10
Completion date
Unknown
Last updated
2026-03-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative urinary retention

Interventions

Experimental group:Ropivacaine was heated to 37°C for 15 minutes in a constant-temperature water bath, and 0.5% warmed ropivacaine (12–13 mg) was administered intrathecally for subarachnoid anesthesia
Control Group:Ropivacaine was kept at room temperature (22°C–24°C), and 0.5% room-temperature ropivacaine (12–13 mg) was administered intrathecally.

Sponsors

Affiliated Hospital of Yan 'an University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Age between 18 and 75 years old; 2. ASA I~III grade; 3. BMI between 18.5 kg/m^2 and 23.9 kg/m^2; 4. Knee arthroscopy under subarachnoid anesthesia; 5. Patient informed consent.

Exclusion criteria

Exclusion criteria: 1. Severe diseases of the respiratory, cardiovascular, cerebrovascular, hepatic, or renal systems; 2. Contraindications to spinal canal anesthesia; 3. Presence of urinary tract infection before surgery; 4. History of urinary tract surgery or benign prostatic hyperplasia; 5. Refusal to sign the research informed consent form.

Design outcomes

Primary

MeasureTime frame
Incidence of urinary retention;

Secondary

MeasureTime frame
Proportion of active urination (no reported difficulty urinating, active urination);Proportion of spontaneous urination after intervention (induced by applying hot compress to the bladder area, rinsing the external genitalia with warm water, listening to the sound of flowing water, etc.);Incidence of indwelling catheterization (proportion of indwelling catheterization to total population);Incidence of urethral irritation (postoperative urethral pain and discomfort);Visual Analogue Scale (VAS) Score (at 12, 24, and 48 Hours After Surgery);First Recovery Time of Motor and Sensory Functions;First Functional Exercise Time;First Out-of-Bed Activity Time;Time to Muscle Strength Recovery to Grade 5;First Oral Intake Time;Incidence of nausea and vomiting within 24 hours after surgery;Patient Postoperative Hospital Stay Time;Total Hospital Stay Time;Incidence of Urinary Tract Infection;The highest block level;Whether epidural supplementation is carried out during the operation and the dosage of the supplementary drug.; Onset time of sensory nerve block;Time to First Postoperative Voiding;Interval from ropivacaine subarachnoid injection completion to supine position;

Countries

China

Contacts

Public ContactZhang Erfei

Affiliated Hospital of Yan 'an University

zhangerfei09@126.com+86 138 9117 0975

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 14, 2026