Acute Coronary Syndrome and Cardiac Arrest
Conditions
Interventions
Case group:None
Control group:None
Sponsors
Yingshang Chengdong Hospital (formerly Yingshang First Hospital)
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients admitted to the Department of Cardiology of our institution during the study period who met the diagnostic criteria for acute coronary syndrome (UA/STEMI/NSTEMI) according to the Chinese Guidelines for the Diagnosis and Treatment of Acute Coronary Syndrome. 2. For patients with ACS complicated by CA, the causal relationship between CA and ACS must be confirmed (CA occurring within 24 hours after the onset of ACS symptoms). 3. Age between 18 and 75 years, regardless of sex. 4. Possessing basic communication ability and willing to provide written informed consent.
Exclusion criteria
Exclusion criteria: 1. Severe hepatic or renal dysfunction (hepatic function: ALT/AST > 3 × upper limit of normal; renal function: eGFR < 30 mL/min/1.73 m²). 2. History of severe infection (e.g., pneumonia, sepsis) or use of immunosuppressive agents (e.g., glucocorticoids, cyclosporine) within 1 month prior to enrollment. 3. Presence of hematological diseases (e.g., leukemia, aplastic anemia) or malignancies. 4. Pregnant or lactating women. 5. Patients with psychiatric disorders or those unable to cooperate with data collection and follow-up. 6. Patients with incomplete clinical data (e.g., coronary angiography reports, medication records).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The correlation between the level of TNFRSF9 in the peripheral blood of ACS patients and the severity of coronary artery stenosis; | — |
Secondary
| Measure | Time frame |
|---|---|
| The differences in TNFRSF9 and cytokine levels between ACS patients with concurrent CA and those without concurrent CA;The differences in TNFRSF9 and cytokine levels between survivors and deceased patients 28 days after CA resuscitation; | — |
Countries
China
Contacts
Public ContactYang Haibing
Yingshang Chengdong Hospital (formerly Yingshang First Hospital)
Outcome results
None listed