Breast cancer
Conditions
Interventions
Treatment Group:Transcutaneous auricular vagus nerve stimulation (taVNS)
Sponsors
The First Medical Center of Chinese PLA General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years. 2. Scheduled to undergo elective breast cancer resection surgery. 3. American Society of Anesthesiologists (ASA) physical status classification of I-III. 4. The patient or their authorized legal representative voluntarily signs the informed consent form, agrees to participate in this study, and cooperates to complete the collection of all observation indicators.
Exclusion criteria
Exclusion criteria: 1. Presence of other interfering factors for cognitive assessment, with a preoperative Mini-Mental State Examination (MMSE) score < 24; severe language communication barriers, hearing impairment, or visual impairment that cannot be compensated for with auxiliary means to cooperate with the assessment. 2. Previous diagnosis of cognitive or psychiatric disorders such as dementia, Parkinson's disease, schizophrenia, bipolar disorder, or major depressive disorder; long-term use of antipsychotics, anxiolytics/antidepressants, sedative-hypnotics, or other medications affecting mental status that cannot be discontinued or adjusted. 3. Presence of skin lesions, infections, ulcers, keloids, severe dermatitis, or congenital ear deformities in both ears that prevent effective fixation of taVNS electrodes; history of ear surgery or ear nerve injury; allergy to taVNS electrode materials or conductive gel. 4. Comorbid severe arrhythmia; implanted electronic devices such as cardiac pacemakers, implantable cardioverter defibrillators, or deep brain stimulators. 5. Participation in other interventional clinical studies within the past 3 months; other circumstances deemed by the investigator as unsuitable for inclusion in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of depressive symptoms; | — |
Secondary
| Measure | Time frame |
|---|---|
| incidence of anxiety symptoms;postoperative nausea and vomiting;postoperative pain score;postoperative sleep quality;time to first postoperative flatus and defecation; | — |
Countries
China
Contacts
Public ContactWeidong Mi
The First Medical Center of Chinese PLA General Hospital
Outcome results
None listed