Hepatocellular Carcinoma (HCC)
Conditions
Interventions
Intervention Group:Intervention Group:Receive targeted immunotherapy + structured mindfulness-based psychological intervention (once every two weeks for 8 weeks). At month 1, month 2, and month 3, fol
Control Group:Control group: Receiving standard targeted immunotherapy, completing GAD-7 and PHQ-9 assessments, as well as multimodal data collection using the "Shouwang" non-contact physiological and
Sponsors
Cancer Hospital, Chinese Academy of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: (1) Aged over 18 years; (2) Diagnosed with hepatocellular carcinoma (HCC) by pathology or clinical criteria; (3) Complete clinical data and medical history; (4) Completed primary school education or above, to ensure the accuracy of questionnaire assessments; (5) All patients and their families signed informed consent prior to treatment, allowing retrospective review and reporting of medical records.
Exclusion criteria
Exclusion criteria: (1) History of mental illness or autoimmune disease; (2) Presence of other malignant tumors; (3) Severe cardiovascular, cerebrovascular, pulmonary, hepatic, renal disease or other organ failure; (4) Previous receipt of similar psychological intervention or targeted immunotherapy; (5) Patients identified with suicidal tendency during psychological screening.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Objective Response Rate (ORR); | — |
Secondary
| Measure | Time frame |
|---|---|
| Progression-Free Survival (PFS);Disease-Free Survival (DFS);Overall Survival (OS);Quality of Life (QoL);Effectiveness of psychotherapy;Model Accuracy; | — |
Countries
China
Contacts
Public ContactZeng Hongmei
Cancer Hospital, Chinese Academy of Medical Sciences
Outcome results
None listed