coronary heart disease
Conditions
Interventions
Sponsors
Shanghai University of Traditional Chinese Medicine Affiliated Shuguang Hospital Anhui Branch
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Meet the following Western medical diagnostic criteria: Based on the joint report of the International Society and Federation of Cardiology and the World Health Organization's Task Force on Standardization of Clinical Nomenclature, "Nomenclature and Criteria for Diagnosis of Ischemic Heart Disease", the study subjects are stable angina pectoris, unstable angina pectoris, and acute myocardial infarction of coronary heart disease. (1) Angina pectoris Exertional angina pectoris: A brief episode of chest pain induced by exercise or other conditions that increase myocardial oxygen demand is called exertional angina pectoris. The pain usually subsides or disappears quickly after rest or sublingual administration of nitroglycerin. It can be further classified into three types: Initial exertional angina pectoris: The course of exertional angina pectoris is within one month. Stable exertional angina pectoris: The course of exertional angina pectoris lasts for one month or more. Worsening exertional angina pectoris: The frequency, severity, and duration of chest pain induced by the same degree of exertion suddenly increase. Spontaneous angina pectoris: Spontaneous angina pectoris is a chest pain episode that has no obvious relationship with an increase in myocardial oxygen demand. Compared with exertional angina pectoris, this type of pain is more severe, lasts longer, and is difficult to relieve with nitroglycerin. The electrocardiogram often shows temporary ST segment depression or T wave changes. Spontaneous angina pectoris can occur alone or coexist with exertional angina pectoris. Some patients with spontaneous angina pectoris have transient ST segment elevation during an attack, which is called variant angina pectoris. However, such electrocardiogram changes recorded in the early stage of myocardial infarction cannot be used for the diagnosis of variant angina pectoris. The above types of angina pectoris, including initial exertional angina pectoris, worsening exertional angina pectoris, and spontaneous angina pectoris, are collectively referred to as "unstable angina pectoris". (2) Acute myocardial infarction The diagnosis of acute myocardial infarction is generally made based on medical history, electrocardiogram, and changes in serum enzymes. If there are definite myocardial enzyme and/or definite electrocardiogram changes, the diagnosis of acute myocardial infarction can be made regardless of whether the medical history is typical or atypical. Specifically: Medical history: Severe and persistent chest pain, but sometimes the chest pain can be mild or absent. Electrocardiogram: Abnormal and persistent ST segment or T wave changes, accompanied by progressive injury current for more than one day. These are definite electrocardiogram changes. Some cases also have indefinite electrocardiogram changes, including static injury current, symmetrical T wave inversion, single pathological Q wave, and conduction disorders. Serum enzymes: Definite changes in serum enzymes include sequential changes in concentration, or initial increase and subsequent decrease. These changes are related to the type of enzyme and the time interval between blood draws. In addition, an increase in cardiac-specific isoenzymes is a definite change. Indefinite changes are an initial increase without subsequent decrease. (3) Coronary heart disease coronary angiography diagnostic criteria: According to the results of coronary angiography, the lumen stenosis degree of
Exclusion criteria
Exclusion criteria: 1.Patients with critical and acute diseases such as acute pericarditis, acute myocarditis, and cardiac tamponade. 2. Patients with severe shock, as well as those with severe primary diseases in the liver, kidneys, and hematopoietic system. 3. Pregnant or lactating women. 4.Patients with mental disorders who cannot cooperate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| major cardiovascular events; | — |
Countries
China
Contacts
Public ContactZhou Hua
Shanghai University of Traditional Chinese Medicine Affiliated Shuguang Hospital Anhui Branch
Outcome results
None listed