Skin aging
Conditions
Interventions
experimental group:Test samples used after picosecond treatment
control group:Use control samples after picosecond treatment
Sponsors
Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: 1.Age over 18 years old, under 60 years old, healthy population, regardless of gender, no history of serious cardiovascular, digestive, endocrine, immune, nervous system or other major diseases, no history of mental or psychological abnormalities; 2.Mild to severe enlarged pores or mild skin laxity on the face, and able to tolerate discomfort during treatment; 3.Willing to read and sign informed consent forms, able to conduct treatment, data collection, and cooperate with visits in accordance with research requirements; 4.Accept to use only the skin care products provided by the sponsor throughout the entire research process, not to use other skin care products, and not to perform any beauty treatments in the beauty salon; 5.The study participants received strict sun protection measures throughout the entire research process, such as sunglasses, hats, umbrellas, masks, etc; 6.The study participants have not undergone any medical beauty treatments in the past 3 months, have not participated in any clinical studies in the past 1 month, and will not undergo any medical beauty treatments or participate in any other clinical trials throughout the study period;
Exclusion criteria
Exclusion criteria: 1.Pregnant and lactating women who changed, started, or stopped oral contraceptives or any hormone therapy within 1.5 months prior to the start of the study; 2.Study participants with active skin diseases, skin infections, skin tumors, psoriasis, rosacea, seborrheic dermatitis, and severe psoriasis; 3.The study participants are currently taking or have been regularly taking systemic or local corticosteroids, vasoconstrictors, antibiotics, and anti-inflammatory drugs within one month prior to the start of the study; 4.Study participants had a history of acute or chronic skin diseases and physical diseases (such as skin cancer, diabetes, asthma, hypertension, hyperthyroidism or hypothyroidism); 5.History of allergies to drugs and cosmetics, especially to local anesthetics; 6.Individuals with a clear history of sun exposure, phototherapy, chemical peels, or those who cannot strictly protect themselves from the sun after treatment within one month; 7.Research participants who frequently engage in outdoor activities such as sunbathing and outdoor work; 8.There are other factors that affect the observation of therapeutic efficacy;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TEWL; | — |
Secondary
| Measure | Time frame |
|---|---|
| skin radiance;Skin moisture content;Skin melanin/hemoglobin;Skin texture image;Skin hyperspectral image;Overall facial photography;skin color; | — |
Countries
China
Contacts
Public ContactDong Jiying
Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine
Outcome results
None listed