Gallbladder carcinoma (GBC)
Conditions
Interventions
Laparoscopic SURGERY Group:mini invasive Laparoscopic SURGERY
Sponsors
The second Affiliated Hospital of Kunming Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Chinese citizens aged >=18 and <=75 years old; 2. Highly suspected or pathologically confirmed gallbladder cancer; 3. Acceptable radical surgery after multidisciplinary comprehensive evaluation; 4. Without preoperative anti-tumor chemoradiotherapy and biological targeted therapy; 5. The subjects understood and could cooperate with this study, and signed the informed consent; 6. On the basis of available evidence or investigator assessment, the patient would benefit from the therapeutic procedure.
Exclusion criteria
Exclusion criteria: 1. Concomitant diseases that, according to the investigator's judgment, seriously endanger the patient's safety or prevent the patient from completing the study; 2. The expected survival time is less than 3 months; 3. Unwilling to sign informed consent or unable to comply with the requirements of the study; 4. Patients with distant metastasis confirmed before or during operation: abdominal implantation, distant lymph node metastasis, liver or other organ metastasis, etc. Abdominal imaging data were used to evaluate patients with vascular invasion or intraoperative combined vascular resection. 5. The subjects received palliative surgery (R2) or other surgical methods; 6. According to the comprehensive judgment of the researcher, it is not suitable to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Complete cure resection rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| intraoperative blood loss;Lymph node dissection status;Duration of the surgery;tumor marker;Postoperative complication rate;90-day unplanned readmission rate; ICU length of stay;Postoperative blood transfusion;Tme to ambulation; Time to resumption of oral intake;Time to drain removal;Surgical cost;;Hospitalization cost;Time to initiation of subsequent adjuvant therapy;Postoperative drainage volume and amylase level.;1-year survival rate;;5-year survival rate;Overall survival (OS); | — |
Countries
China
Contacts
Public ContactDong Wei
The second Affiliated Hospital of Kunming Medical University
Outcome results
None listed