None listed
Conditions
Interventions
Experimental Group:Early emergency cervical cerclage
Control Group:Delayed emergency cervical cerclage
Sponsors
Fujian Maternity and Child Health Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Singleton pregnant women in the mid-trimester (gestational age 14+0 to 27+6 weeks). 2. Painless cervical dilation >=1 cm, with or without membrane protrusion. 3. The pregnant woman and her family members are fully informed, voluntarily agree to participate in this study, and have signed the informed consent form. 4. Age >=18 years and <=45 years, with normal cognitive ability.
Exclusion criteria
Exclusion criteria: 1. Presence of contraindications for cervical cerclage: such as preterm premature rupture of membranes (PPROM) before the procedure, active vaginal bleeding, clinically diagnosed chorioamnionitis (body temperature >=38°C, fetal tachycardia, purulent vaginal discharge with elevated white blood cell count), fetus with severe congenital malformations or genetic diseases, or intrauterine fetal death. 2. Candidates for or recipients of Shirodkar cerclage or laparoscopic cerclage. 3. Poor compliance, unable to cooperate with postoperative follow-up. 4. Pregnant women who refuse tocolytic therapy. 5. Iatrogenic preterm birth. 6. Incomplete clinical data. 7. Coexisting severe medical or surgical diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Preterm birth rate before 32 weeks; | — |
Secondary
| Measure | Time frame |
|---|---|
| Preterm birth rates at specified gestational ages (<28, <34, <37 weeks);Neonatal survival rate;Neonatal NICU admission rate;Neonatal birth weight (grams);Incidence of maternal complications (PPROM, chorioamnionitis, postpartum hemorrhage, etc.);Incidence of neonatal complications (NEC, IVH, sepsis, RDS, etc.);Prolongation of pregnancy (days); | — |
Countries
China
Contacts
Public ContactMian Pan
Fujian Maternity and Child Health Hospital
Outcome results
None listed