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A prospective, multicenter, randomized, controlled, single-blind, superiority trial: evaluating the use of Tubeless VATS in lobectomy

A prospective, multicenter, randomized, controlled, single-blind, superiority trial: evaluating the use of Tubeless VATS in lobectomy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600119852
Enrollment
Unknown
Registered
2026-03-04
Start date
2026-03-16
Completion date
Unknown
Last updated
2026-03-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung cancer

Interventions

Experimental group:A minimally invasive surgical plan that uses a laryngeal mask to maintain ventilation, preserves spontaneous breathing, and aims to avoid leaving a chest drainage tube after the ope
Control group:A minimally invasive surgical plan was adopted, which involved standard tracheal intubation for single-lung ventilation and routine postoperative placement of thoracic drainage tubes.

Sponsors

Fujian Medical University Union Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Sign the informed consent form; 2. Due to lung cancer and irreversible pathological changes that are unresponsive to long-term drug conservative treatment (severe bronchiectasis, chronic lung abscess, certain types of pulmonary tuberculosis, damaged lungs), a lobectomy of the lung is required; 3. Age (18-70 years old); 4. ECOG score 70%, PaO2 >= 75 mmHg and PaCO2 < 45 mmHg

Exclusion criteria

Exclusion criteria: 1. Patients who refuse the surgical and/or anesthesia plan; 2. Coagulopathy, hypoxemia (PaO2 50 mmHg, or increased reflux risk due to preoperative or gastroesophageal reflux disease (fasting < 6 hours); neurological disorders; 3. Severe acute pulmonary infection or pulmonary tuberculosis; 4. Relative contraindications: upper respiratory tract secretions or persistent cough, spinal deformity or brain edema (if using thoracic epidural anesthesia); 5. Diaphragmatic nerve palsy on the non-surgical side should be regarded as a contraindication for VATS; 6. Important history of heart disease; 7. Local anesthesia allergy; 8. Any contraindications to local anesthesia techniques; 9. Difficult airway management; 10. Preoperative pleural effusion; emphysema, residual bullae.

Design outcomes

Primary

MeasureTime frame
Postoperative hospital stay;

Secondary

MeasureTime frame
Time of first feeding;Conversion to thoracotomy;Intraoperative blood loss;Anesthesia-related complications;The time of first ambulation;Operation time;Drainage tube removal time;Daily drainage volume;Postoperative Pain Score;Incidence of Postoperative complications;

Countries

China

Contacts

Public ContactChen Shuchen

Fujian Medical University Union Hospital

cscdoctor@163.com+86 591 86218010

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 14, 2026