Patients with low-weight gastrointestinal tumors
Conditions
Interventions
Group P (General anesthesia induction and maintenance were carried out using propofol):None
Group C (Cyclopofol was used for general anesthesia induction and maintenance):None
Sponsors
Guangxi Medical University Cancer Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: 1. Age range: 18 - 64 years; 2. BMI < 18.5 kg/m²; 3. Undergo elective laparoscopic surgery for gastrointestinal tumors; 4. ASA grade II or III; 5. No obvious dysfunction of important organs such as the heart, lungs, liver, and kidneys; 6. Undergo general anesthesia. The intraoperative anesthesia maintenance plan (including whether to use inhalation anesthetics and the specific types and doses) is determined by the anesthesiologist based on the clinical situation and is recorded in detail.
Exclusion criteria
Exclusion criteria: 1.Those who have been using drugs that affect the central nervous system or blood circulation for a long time and have not discontinued them before the operation; 2.Those who are known to be allergic to propofol, etomidate, or the components of their fat emulsion products; 3.The main anesthesia maintenance drug regimen was changed during the operation. 4.The medical records are severely lacking (for instance, key vital sign data is lost by more than 20%). 5.The preoperative hemodynamic condition was extremely unstable, and large doses of vasoactive drugs were required to maintain it.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of intraoperative hypotension; | — |
Secondary
| Measure | Time frame |
|---|---|
| The incidence of adverse events during the patient's stay in the post-anesthesia care unit (PACU);The cumulative duration of intraoperative hypotension in the two groups of patients;The time of extubation after the patient's surgery;The usage rate and total dosage of vasoactive drugs in the two groups of patients;The incidence of severe respiratory depression during the induction period (with SpO? < 90% or requiring mask-assisted ventilation);The incidence of injection pain during the induction period of anesthesia;The postoperative awakening time of the patient (from the cessation of all anesthetic drugs to the moment of opening eyes upon being called); | — |
Countries
China
Contacts
Public ContactWang Qiang
Guangxi Medical University Cancer Hospital
Outcome results
None listed