Multimorbidity and Polypharmacy
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged >=65 years and <90 years, regardless of sex; 2. Scheduled for elective non-cardiac surgery with an American Society of Anesthesiologists (ASA) physical status classification of I to III; 3. Voluntarily participated and signed the informed consent form, had complete clinical data, and were able to complete the follow-up visits.
Exclusion criteria
Exclusion criteria: Refusal to participate in this study; dementia; inability to communicate preoperatively due to coma, audiovisual disturbances, or language disorders; pre-existing diagnosis of schizophrenia, epilepsy, Parkinson's disease, or myasthenia gravis; severe cardiac, cerebral, renal, or hepatic dysfunction, or craniocerebral injury; patients undergoing emergency or intracranial surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative delirium within 3 days after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Preoperative Frailty Phenotype by Fried;Postoperative Day 3 QoR-15 Score;Length of hospital stay;Postoperative mortality at 30 days;One-year mortality; | — |
Countries
China
Contacts
The Second Affiliated Hospital of Nanjing Medical University