Late-life depression
Conditions
Interventions
Treatment Group:In addition to SSRI medication, combined with transcranial direct current stimulation (tDCS) and cognitive digital therapy training. tDCS parameters: anode stimulation at the left dors
Control Group:In addition to SSRI medication, combined with sham stimulation (Pseudo-tDCS) and cognitive digital therapy training. Sham stimulation procedure: 30 seconds of electrical stimulation foll
Sponsors
The Third People's Hospital,Ganzhou
Eligibility
Sex/Gender
All
Age
60 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age >= 60 years old 2. Meet the ICD-10 diagnostic criteria for depression 3. HAMD-17 score >= 17 points (baseline period) 4. Participate voluntarily and sign the informed consent form 5. No severe cognitive impairment (MMSE>=24 points)
Exclusion criteria
Exclusion criteria: 1.Have a history of other major mental illnesses (such as schizophrenia, bipolar disorder, etc.) 2. Suffering from severe physical illness or instability (such as serious heart, liver or kidney diseases) 3. Have a history of epilepsy or have metal implants in the brain 4. Recently (within 3 months) received electroconvulsive therapy (MECT) or tDCS. 5. Currently participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in patient depressive symptoms; | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in patient cognitive function and quality of life; | — |
Countries
China
Contacts
Public ContactGuo Longrun
The Third People's Hospital,Ganzhou
Outcome results
None listed