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To investigate the correlation between renal tissue injury and retinal microcirculation in patients with chronic kidney disease

To investigate the correlation between renal tissue injury and retinal microcirculation in patients with chronic kidney disease

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600119797
Enrollment
Unknown
Registered
2026-03-03
Start date
2026-03-03
Completion date
Unknown
Last updated
2026-03-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Renal tissue injury and retinal microcirculation in patients with chronic kidney disease

Interventions

Patients with chronic kidney disease:None

Sponsors

Shanghai General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Satisfying the clinical diagnostic criteria for chronic kidney disease. 2.The subjects had undergone kidney-related examinations within one month of completing the ophthalmology examinations. 3.Gender is not limited. Age should be at least 18 years old. 4.The written informed consent form approved by the Ethics Committee of Shanghai General Hospital shall be signed by the subject or the legal representative and dated.

Exclusion criteria

Exclusion criteria: 1.Suffering from any eye disease that affects the blood circulation of the retinal and choroid. 2.History of ocular treatment or history of cataract surgery within 3 months. 3.Turbidity of refractive media leads to poor image quality and unreliable data in eye examinations. 4.Diabetes mellitus. 5.Serious systemic disease. 6.If the subject or the legal representative refuses to sign the written informed consent form approved by the Ethics Committee of Shanghai General Hospital.

Design outcomes

Primary

MeasureTime frame
eGFR;ACR;vessel density;perfusion density;choroidal vascularity index,CVI;

Secondary

MeasureTime frame
foveal avascular zone area,FAZa;foveal avascular zone perimeter,FAZp;foveal avascular zone circularity,FAZc;choroidal vessel volume,CVV;choroidal stroma index,CSI;choroidal volume fraction,CSV;choroidal thickness,ChT;

Countries

China

Contacts

Public ContactXiaolu Yang

Shanghai General Hospital

dryangxiaolu@163.com+86 153 1731 4398

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 14, 2026