Renal tissue injury and retinal microcirculation in patients with chronic kidney disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Satisfying the clinical diagnostic criteria for chronic kidney disease. 2.The subjects had undergone kidney-related examinations within one month of completing the ophthalmology examinations. 3.Gender is not limited. Age should be at least 18 years old. 4.The written informed consent form approved by the Ethics Committee of Shanghai General Hospital shall be signed by the subject or the legal representative and dated.
Exclusion criteria
Exclusion criteria: 1.Suffering from any eye disease that affects the blood circulation of the retinal and choroid. 2.History of ocular treatment or history of cataract surgery within 3 months. 3.Turbidity of refractive media leads to poor image quality and unreliable data in eye examinations. 4.Diabetes mellitus. 5.Serious systemic disease. 6.If the subject or the legal representative refuses to sign the written informed consent form approved by the Ethics Committee of Shanghai General Hospital.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| eGFR;ACR;vessel density;perfusion density;choroidal vascularity index,CVI; | — |
Secondary
| Measure | Time frame |
|---|---|
| foveal avascular zone area,FAZa;foveal avascular zone perimeter,FAZp;foveal avascular zone circularity,FAZc;choroidal vessel volume,CVV;choroidal stroma index,CSI;choroidal volume fraction,CSV;choroidal thickness,ChT; | — |
Countries
China
Contacts
Shanghai General Hospital