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Study on the Value of Ultrasound Myocardial Strain in Differentiating Left Ventricular Hypertrophy Diseases

Study on the Value of Ultrasound Myocardial Strain in Differentiating Left Ventricular Hypertrophy Diseases

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600119788
Enrollment
Unknown
Registered
2026-03-03
Start date
2026-03-03
Completion date
Unknown
Last updated
2026-03-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with left ventricular hypertrophy include hypertrophic cardiomyopathy, cardiac amyloidosis, and hypertensive heart disease.

Interventions

Observation group:NA

Sponsors

Ganzhou people's hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.HCM group: All meet the diagnostic criteria of the American Heart Association guidelines. 1Those diagnosed with pathological genetic variations through genetic testing; 2 Left ventricular hypertrophy: Maximum diastolic end wall thickness > 15 mm; 2.or maximum diastolic end wall thickness > 11 mm along with a family history of HCM, or a history of sudden death, or genetic mutations, or accompanied by left ventricular outflow tract obstruction; 3.special segment wall hypertrophy cases. (2) HHD group: 1With a long-term history of hypertension [systolic blood pressure >= 150 mmHg or diastolic blood pressure >=90 mmHg for more than 5 years]; 2Left ventricular hypertrophy detected by echocardiography, maximum diastolic end wall thickness > 11 mm. (3) CA group: 1. Confirmed by endomyocardial biopsy pathology;2. Or confirmed by biopsy pathology from other organs outside the heart;3. Involving the heart, left ventricular wall thickness > 11 mm. Age: >=18 years Gender: No restriction Patient inclusion criteria: Individuals diagnosed with hypertrophic cardiomyopathy, cardiac amyloidosis, or hypertensive heart disease at Ganzhou People's Hospital between January 2022 and May 2024. Requirement: Complete clinical documentation available.

Exclusion criteria

Exclusion criteria: 1.Include coronary heart disease, valvular disease, and congenital heart disease; 2.New York Heart Function Classification Grade IV; 3. Complicated with other systemic diseases or infiltrative cardiomyopathy; 4.Previous history of ventricular septal ablation or hypertrophic cardiomyectomy surgery.

Design outcomes

Primary

MeasureTime frame
Left ventricular global longitudinal strain;Left ventricular global circumferential strain;17-segment strain peak value bull's eye plot;;17-segment time-to-peak bull's eye plot;

Countries

China

Contacts

Public ContactCuicui Zhou

Ganzhou people's hospital

zhoucuicui@mail.gzsrmyy.com+86 797 588 9208

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 14, 2026