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A Retrospective Clinical Study of Microvascular Decompression for Nonaneurysmal Vascular Compression–Induced Oculomotor Nerve Palsy

A Retrospective Clinical Study of Microvascular Decompression for Nonaneurysmal Vascular Compression–Induced Oculomotor Nerve Palsy

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600119773
Enrollment
Unknown
Registered
2026-03-03
Start date
2026-03-15
Completion date
Unknown
Last updated
2026-03-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oculomotor nerve palsy

Interventions

Observation group:None

Sponsors

Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients who underwent microvascular decompression of the oculomotor nerve between January 1, 2020, and November 31, 2025, with the following surgical criteria: (1) Patients presenting with diplopia, restricted eye movement, ptosis, or impaired pupillary constriction (meeting one or more of these conditions); (2) Neuroimaging confirmed the presence of vascular-nerve conflict affecting the oculomotor nerve (non-aneurysmal); (3) Willingness to undergo microvascular decompression of the oculomotor nerve. 2. Complete postoperative follow-up data available for analysis.

Exclusion criteria

Exclusion criteria: 1. Incomplete medical record data, follow-up time less than 3 months; 2. History of severe dementia, schizophrenia and other mental illnesses; 3. Have a history of drugs or drug addiction; 4. History of severe systemic diseases, especially circulatory diseases: such as myocardial infarction, heart failure, unstable angina.

Design outcomes

Primary

MeasureTime frame
Grading of oculomotor nerve palsy recovery;

Secondary

MeasureTime frame
Changes in the Oculomotor Nerve Palsy - Eyelid Function Scoring;Changes in the Pupillary Function Score of Oculomotor Nerve Palsy;

Countries

China

Contacts

Public ContactShiting Li

Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine

lishiting@xinhuamed.com.cn+86 21 2507 8001

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 14, 2026