Papillary Thyroid Carcinoma with Cervical Lymph Node Metastasis
Conditions
Interventions
Gold Standard:Surgical histopathology or FNA pathology.
Index test:· Basic ultrasound information of thyroid nodules and lymph nodes· Microvascular flow ( Quantitative microvascular flow analysis)· Elastography (quantitative indices of shear wave and visco
Sponsors
The First Affiliated Hospital of Xi'an Jiaotong University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age greater than 18 years; 2. Presence of suspicious papillary thyroid carcinoma nodule(s) with at least one lymph node detected in level VI, with or without suspicious lymph nodes in the lateral neck; 3. Availability of satisfactory images of the target nodule obtained from conventional ultrasound, elastography, and HoloUMA; 4. Confirmed diagnosis of papillary thyroid carcinoma in the thyroid nodule by FNA or histopathology, and confirmed pathological results (by FNA or surgical excision) for all suspicious lymph nodes.
Exclusion criteria
Exclusion criteria: 1. Patients with incomplete clinical data due to not undergoing surgery/FNA at our hospital; 2. Patients without a definitive pathological diagnosis; 3. Patients with concurrent malignancy in other organs; 4. Patients with a history of thyroid nodule ablation; 5. Patients with a history of neck irradiation or a family history of thyroid cancer.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Shear wave elastic hardness: E (kPa);Sum of Angle Metric;Distance Metric;Vessel Density;Flow Perfusion index;Viscosity coefficient;Number of Branch Per Area;Number of Branch Points Per Area;Dispersion coefficient;Flow Weighted Vessel Density;Area under the receiver operating characteristic curv;Pathological findings (surgical pathology or fine needle aspiration); | — |
Secondary
| Measure | Time frame |
|---|---|
| Ultrasonic features of thyroid nodules and lymph nodes;Positive Predictive Value;Sensitivity;Negative Predictive Value;Specificity; | — |
Countries
China
Contacts
Public ContactRuan Litao
The First Affiliated Hospital of Xi'an Jiaotong University
Outcome results
None listed