Holmium Laser Lithotripsy
Conditions
Interventions
Ciprofol group:Anesthesia induction: Administer sufentanil 0.2–0.4 µg/kg, propofol 0.3–0.4 mg/kg, and rocuronium 0.6 mg/kg intravenously in sequence. Tracheal intubation or laryngeal mask insertion is
Propofol group:Anesthesia induction: Administer sufentanil 0.2–0.4 µg/kg, propofol 1.5–2.5 mg/kg, and rocuronium 0.6 mg/kg intravenously in sequence. Perform tracheal intubation or laryngeal mask inse
intraoperative circulation management and postoperative handling are the same as the cyclopropane propofol group.
Sponsors
Department of Anesthesiology, The First Affiliated Hospital of Henan University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >=18 years, planned to undergo elective transurethral holmium laser lithotripsy; 2. Meet the diagnostic criteria for frailty (modified frailty index mFI >=0.27); 3. ASA classification II~IV; 4. Body mass index (BMI) 18~30 kg/m^2; 5. No contraindications to general anesthesia; 6. Clearly understand the study content and voluntarily participate in this study, signing the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Allergy to propofol, propofol-lipid formulations, or drugs related to this study (such as sufentanil, rocuronium, etc.); 2. Severe heart, lung, liver, or kidney dysfunction (Child-Pugh class C, eGFR =1 month); 5. Combined with cranial injury or intracranial hypertension; 6. Unable to cooperate with cognitive assessment or having communication disorders; 7. Expected surgery time 2 hours.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood Pressure;Postoperative Recovery Quality;Heart Rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Oxygen Saturation;Bispectral Index value; | — |
Countries
China
Contacts
Public ContactYing Wang
The First Affiliated Hospital of Henan University
Outcome results
None listed