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A Multimodal Study on Postoperative Changes in Visual Perceptual Function and Brain Activity in Patients with Glaucoma and Cataract

A Multimodal Study on Postoperative Changes in Visual Perceptual Function and Brain Activity in Patients with Glaucoma and Cataract

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600119743
Enrollment
Unknown
Registered
2026-03-03
Start date
2026-03-09
Completion date
Unknown
Last updated
2026-03-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cataract?glaucoma

Interventions

Patients with coexisting glaucoma and cataract group:None

Sponsors

Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1.Age 50 to 85 years old (including 50 and 85 years old), no gender restrictions; 2.Meet the diagnostic criteria for glaucoma and cataracts; 3.Patients scheduled for cataract phacoemulsification with intraocular lens implantation, who may also undergo concomitant glaucoma-related procedures (e.g., trabeculectomy, goniotomy, or drainage device implantation); 4.Able and willing to adhere to all follow-up schedules; 5.Voluntarily agree to participate in this study and provide written informed consent, unless exempted from informed consent following ethics committee approval.

Exclusion criteria

Exclusion criteria: 1.Systemic diseases that may affect postoperative outcomes, such as patients with unstable blood glucose control in diabetes; 2.Amblyopia, strabismus, corneal diseases, severe retinal diseases, and other ocular conditions that may compromise postoperative results; 3.History of ocular trauma or prior ocular surgeries that may confound observation findings; 4.Pregnant or lactating women; 5.Current or past history of traumatic brain injury, cerebrovascular disease (e.g., stroke), neurological disorders (e.g., epilepsy, Alzheimer's disease, Parkinson's disease), or psychiatric conditions (e.g., depression, schizophrenia); 6.History of alcohol dependence or substance abuse; 7.Presence of depressive symptoms, intellectual impairment, dementia symptoms, or sleep disorder symptoms; 8.Working memory capacity below 3 or inability to complete working memory tasks; 9.Claustrophobia or metallic implants that do not meet MRI safety standards; 10.Inability to comply with follow-up appointments as directed; 11.Other circumstances where the investigator determines the patient is unsuitable for enrollment;

Design outcomes

Primary

MeasureTime frame
Functional Magnetic Resonance Imaging (fMRI);Electroencephalography (EEG) data;

Secondary

MeasureTime frame
Changes in visual acuity, subjective refraction, intraocular pressure, slit-lamp examination, and iTrace examination results compared to pre-operation;

Countries

China

Contacts

Public ContactGuo Tao

Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine

guotao9@hotmail.com+86 21 23271699

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 14, 2026