Frailty in elderly patients
Conditions
Interventions
Sponsors
Suining Central Hospital
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >= 65 years; 2. Scheduled for routine painless gastrointestinal endoscopy at Suining Central Hospital; 3. Undergoing intravenous sedation anesthesia with propofol or ciprofol; 4. Able to complete preoperative cognitive assessment (MMSE = 23); 5. Complete perioperative monitoring data (mean arterial pressure, heart rate, SpO2, etc.); 6. Informed consent was obtained from the patient and their family members;
Exclusion criteria
Exclusion criteria: 1. Severe organic diseases (e.g., NYHA Class III or above heart failure, unstable angina, recent myocardial infarction within 3 months, severe COPD, severe liver/kidney dysfunction; 2. History of moderate/severe cognitive impairment, psychiatric disorders, or inability to complete cognitive assessment. 3. Preoperative acute conditions affecting circulatory stability (e.g., infection, high fever, electrolyte disorders). 4. Incomplete anesthesia or monitoring data, missing key parameters (e.g., BP, HR, SpO2). 5. Serious intraoperative adverse events resulting in unusable data; 6. Refusal to provide informed consent or withdrawal from the study during participation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean arterial pressure variability (?MAP); | — |
Secondary
| Measure | Time frame |
|---|---|
| Intraoperative Vital Signs Changes;Recovery Time from Anesthesia (Including Awakening Time and Discharge Time);Incidence of Postoperative Adverse Events;Number Cancellation Test, NCT;Postoperative Cognitive Function; | — |
Countries
China
Contacts
Public ContactJinping Wang
Suining Central Hospital
Outcome results
None listed