alzheimer disease
Conditions
Interventions
Group with BPSD symptoms in AD :None
Group without BPSD symptoms in AD:None
Sponsors
Chengdu Fourth People's Hospital
Eligibility
Sex/Gender
All
Age
55 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Meets the diagnostic criteria for AD as stipulated in the Fifth Edition of the Diagnostic and Statistical Manual of Mental Disorders of the American Psychiatric Association; 2. Age >= 55 years; 3. Voluntary participation or consent from the family members for this study.
Exclusion criteria
Exclusion criteria: 1. Exclude individuals with severe diseases of vital organs such as the heart, liver, and kidneys. 2. Exclude systemic conditions that can cause dementia, including hypothyroidism, vitamin B complex or folic acid deficiency, niacin deficiency, hypocalcemia, neurosyphilis, and HIV infection. 3. Exclude patients with cognitive impairment caused by prior mental disorders such as depression and schizophrenia. 4. Exclude patients taking cholinesterase inhibitors, benzodiazepines, or antidepressants that may affect electroencephalogram (EEG) rhythms. 5. Exclude patients who received antipsychotic medication within the past month. 6. Exclude those unable to complete the examinations. 6. Questionnaires with 20% or more missing data shall be invalidated.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NeuroPsychiatyicInventory,NPI;Mini-mental State Examination;Eeg quantitative indicators (power spectrum, network attributes);Semiquantitative Visual Rating Scale for Medial Temporal Atrophy (MTA);Semiquantitative Visual Rating Scale for White Matter Lesions (Fazekas Scale); | — |
Countries
China
Contacts
Public ContactLi Zhang
Chengdu Fourth People's Hospital
Outcome results
None listed