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Alterations in renal microcirculatory perfusion and renal response to fluids before and after rapid rehydration in critically ill acute oliguric patients

Alterations in renal microcirculatory perfusion and renal response to fluids before and after rapid rehydration in critically ill acute oliguric patients

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600119726
Enrollment
Unknown
Registered
2026-03-03
Start date
2026-03-15
Completion date
Unknown
Last updated
2026-03-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute kidney injury of sepsis

Interventions

Observation group:None

Sponsors

The First Affiliated Hospital of Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1.18–85 years of age. 2.Within 24 hours of ICU admission, urine output < 30 mL/h for 3 consecutive hours. 3.Requires rapid fluid resuscitation (250 mL fluid administered intravenously over 15 minutes).

Exclusion criteria

Exclusion criteria: 1.Comorbidities included chronic dialysis, renal transplant, renal tumor, multiple renal cysts, renal vascular malformation, and systemic rheumatic immune diseases (e.g., SLE). 2.Patients were excluded if ultrasound image acquisition was limited. 3.baseline cardiac EF < 50%. 4.they were pregnant or postpartum. 5.had a history of contrast allergy.

Design outcomes

Primary

MeasureTime frame
Area under the curve;Peak intensity;Time to peak;—

Countries

China

Contacts

Public ContactChangjie Cai

The First Affiliated Hospital of Sun Yat-sen University

caicj2025@126.com+86 136 5039 9131

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 14, 2026