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Effect of Esketamine Combined with Ropivacaine on Postoperative Recovery and Inflammatory Immune Response in Patients Undergoing Single-Port Laparoscopic Surgery under TAP Block

Effect of Esketamine Combined with Ropivacaine on Postoperative Recovery and Inflammatory Immune Response in Patients Undergoing Single-Port Laparoscopic Surgery under TAP Block

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600119720
Enrollment
Unknown
Registered
2026-03-03
Start date
2026-03-03
Completion date
Unknown
Last updated
2026-03-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain

Interventions

GroupT:0.2% Ropivacaine + NS, total 40 ml
GroupE:0.2% Ropivacaine+ 0.5 mg/kg Esketamine+ NS, total 40 ml

Sponsors

Chengdu Integrated TCM&Western Medicine Hospital (Chengdu first people's Hospital)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Age: 18 - 65 years old, gender not restricted, BMI: 18 - 30 Kg/m^2, ASA classification: II - III. 2. Patients who have undergone single-port laparoscopic surgery. 3. Clearly understand and voluntarily participate in this study, and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. BMI > 30 kg/m^2 ; 2. Those who are allergic or contraindicated to the main experimental drug components; 3. Those with uncontrolled severe heart, lung, liver or kidney diseases; 4. Those with a history of abdominal wall surgery, coagulation dysfunction, or skin infections; 5. Patients currently participating in other clinical trials or those who, in the opinion of the researchers, are not suitable to participate in this trial.

Design outcomes

Primary

MeasureTime frame
Visual analogue scale score;Pittsburgh Sleep Quality Index Score;

Secondary

MeasureTime frame
White blood cell;Systemic Inflammatory Immune Index;

Countries

China

Contacts

Public ContactZuofeng Wang

Chengdu Integrated TCM&Western Medicine Hospital (Chengdu first people's Hospital)

5590786@qq.com+86 181 8077 6670

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 14, 2026