Congenital cystic lung disease
Conditions
Interventions
Conventional ventilation group (group C):The inspiratory/expiratory ratio (I:E) was set at 1:1.5 during one-lung ventilation
Inverse ratio ventilation group (F group):The inspiratory/expiratory ratio (I:E) was 1.5:1 during one-lung ventilation
Sponsors
The Second Affiliated Hospital of Xi 'an Jiaotong University
Eligibility
Sex/Gender
All
Age
No minimum to 1 Years
Inclusion criteria
Inclusion criteria: 1. The guardians of the children signed the informed consent 2. The preoperative diagnosis was congenital cystic lung disease 3. Thoracoscopic pneumonectomy was planned 4. Age from 1 month to 1 year 5. ASA grade I-II
Exclusion criteria
Exclusion criteria: 1. The guardian of the child refused to participate in the study 2. Previous history of asthma 3. Infection within the last two weeks (body temperature = 38.0?, upper respiratory tract infection or chest X-ray suggesting pneumonia) 4. Complicated with congenital heart disease 5. ASA grade >=III 6. Congenital neuropsychiatric disorders, neuromuscular diseases (myasthenia gravis, myasthenic syndrome, Guillain-Barre syndrome, etc.) 7, combined with insufficient nutritional support (mainly including improper feeding, chronic diarrhea, recurrent respiratory tract infection and other diseases affecting nutrition absorption, food allergy, intestinal flora imbalance and other causes of digestive dysfunction) 8. Previous thoracic surgery, phrenic nerve palsy, and airway allergy history
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The ratio of postoperative diaphragmatic excursion to baseline diaphragmatic excursion and the ratio of postoperative diaphragmatic thickening fraction to baseline diaphragmatic thickening fraction were calculated; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of pulmonary complications within 5 days after surgery;Length of stay;Occurrence of postoperative diaphragmatic dysfunction(diaphragmatic excursion,diaphragm thickening fraction);Heart rate (HR), mean arterial pressure (MAP) and blood oxygen saturation (spo2) were measured before anesthesia, 5min after OLV, 1h after OLV, immediately after surgery, and at the time of leaving PACU;Blood gas parameters (partial pressure of oxygen, partial pressure of carbon dioxide, alveolar-arterial oxygen difference, oxygenation index) at 1h after one-lung ventilation, at the end of surgery, and at the time of leaving PACU;Respiratory mechanics parameters (end-tidal carbon dioxide, peak airway pressure, plateau airway pressure, mean airway pressure, positive end-expiratory pressure) at 5min after one-lung ventilation, 1h after one-lung ventilation, and immediately after the end of surgery.; | — |
Countries
China
Contacts
Public ContactLei Xiaoming
The Second Affiliated Hospital of Xi 'an Jiaotong University
Outcome results
None listed