Skin scars
Conditions
Interventions
Observation group:N/A
Sponsors
Shanghai Skin Disease Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Patients aged between 18 and 65, of either gender, who plan to undergo scar excision surgery. The scar formation duration exceeds 6 months and is in a stable phase.
Exclusion criteria
Exclusion criteria: Women who are pregnant or breastfeeding. Those with systemic diseases that affect wound healing (such as uncontrolled diabetes, autoimmune diseases, severe malnutrition, etc.). Scars with active infection, ulceration, or malignancy. Long-term use of drugs that may affect fibrosis (such as systemic glucocorticoids, immunosuppressants, etc.). Scars with a history of radiation therapy. Any other conditions that the investigator deems unsuitable for participation in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| YAP expression level;PYCR1 expression level;a-SMA expression level; | — |
Secondary
| Measure | Time frame |
|---|---|
| CSF1R expression level;CSF1 expression level; | — |
Countries
China
Contacts
Public ContactZongguang Tai
Shanghai Skin Disease Hospital
Outcome results
None listed