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The effect and mechanism of high-precision transcranial electrical stimulation on post-stroke dysfunction

The effect and mechanism of high-precision transcranial electrical stimulation on post-stroke dysfunction

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600119690
Enrollment
Unknown
Registered
2026-03-02
Start date
2026-03-10
Completion date
Unknown
Last updated
2026-03-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Interventions

High-precision transcranial electrical stimulation:With the help of high-channel 10-20 system electrode cap and head magnetic resonance imaging, 2-4 groups of electrode pads were used to perform high-
Control Group:Accept pseudo stimuli. The device will gradually increase the current intensity from 0 to the set value and then decrease to 0 within the first 30 seconds, causing the subject to experie

Sponsors

Zhangzhou Hospital Affiliated to Fujian Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients with cerebral infarction / cerebral hemorrhage in the left hemisphere for the first time confirmed by head computed tomography (CT) or magnetic resonance (MRI) (the diagnosis is in line with the consensus of "key points for the diagnosis of various major cerebrovascular diseases in China 2019" formulated by the cerebrovascular disease group of Neurology branch of Chinese Medical Association); 2. The course of disease was 1-6 months; 3. Brunnstrom stage: hand stage III - V, upper limb stage II - V; Fma-ue score was 8-50; The muscle group above elbow joint was MAS < 2; 4. The AQ was less than 70 by WAB; The mother tongue is Chinese, and the language function is normal before the onset; 5. They were aged 18 to 80 years, with primary school education or above, and were identified as right handers by the standardized questionnaire survey on the distribution of left and right handers in Chinese; 6. The score of non-verbal cognitive function scale is more than 65, which can be used to complete relevant tests; 7. Volunteer to participate in this study and sign informed consent.

Exclusion criteria

Exclusion criteria: 1. Previous history of brain injury, epilepsy, alcohol or drug dependence and other diseases that may affect brain function and structure; 2. Combined with chronic infectious diseases; 3. Metal implants (such as pacemaker) and claustrophobia were contraindications of MRI examination; 4. Patients with Alzheimer's disease, Parkinson's disease and other diseases that affect the rehabilitation evaluation; 5. Malignant tumor, bleeding tendency, active tuberculosis, severe cardiopulmonary insufficiency, pregnancy and other intolerance.

Design outcomes

Primary

MeasureTime frame
Western aphasia test score;FMA-UL score;Montreal Cognitive Assessment, MOCA ;

Secondary

MeasureTime frame
wolf motor function test ;Boston Naming Test;

Countries

China

Contacts

Public ContactShuo Xu

Zhangzhou Hospital Affiliated to Fujian Medical University

xus20@foxmail.com+86 158 5221 4099

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 14, 2026