Pain after video-assisted thoracoscopic surgery in patients with pulmonary tumors
Conditions
Interventions
Group RP:For patients undergoing ultrasound-guided superficial serratus anterior plane block, subjects in the RP group received 0.5% ropivacaine (150 mg, 30 ml)
Group LB :For patients undergoing ultrasound-guided superficial serratus anterior plane block, subjects in the LB group received liposomal bupivacaine (266 mg, diluted to 30 ml)
Sponsors
Beijing Friendship Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients undergoing elective thoracoscopic lung tumor resection under general anesthesia for the first time; 2. Aged 18–65 years, with body mass index (BMI) ranging from 18.5 to 30 kg/m^2, regardless of gender; 3. Classified as American Society of Anesthesiologists (ASA) Physical Status Class ?–?.
Exclusion criteria
Exclusion criteria: 1. Patients who are pregnant. 2. Patients with a history of allergies to anesthetics associated with general anesthesia or nerve block. 3. Patients with a history of chronic pain and long-term oral administration of non-steroidal anti-inflammatory drugs (NSAIDs) or other analgesics. 4. Patients with infection, rash at the chest wall puncture site, or severe coagulation disorders. 5. Patients with severe psychological or psychiatric diseases, or communication disorders. 6. Patients with severe liver dysfunction, whose preoperative alanine aminotransferase (ALT) or aspartate aminotransferase (AST) levels exceed twice the normal value. 7. Patients who have participated in other clinical trials within the past four weeks
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of chronic postsurgical pain at 3-month follow-up; | — |
Secondary
| Measure | Time frame |
|---|---|
| Satisfaction level of participants;Short-term postoperative analgesic efficacy;Intraoperative remifentanil dosage;sufentanil consumption in the patient-controlled analgesia (PCA) pump within 72 hours postoperatively;Total number of patient-controlled analgesia (PCA) pump presses by the subjects within 72 hours postoperatively;Safety indicators;Morphine rescue consumption within 72 hours postoperatively;Time to thoracic drainage tube removal in the subjects;Time to first ambulation after surgery in the subjects;Total hospitalization costs during the subjects' stay;Postoperative length of hospital stay in the subjects; | — |
Countries
China
Contacts
Public ContactAn Lixin
Beijing Friendship Hospital, Capital Medical University
Outcome results
None listed