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Construction and Validation of a Novel Depression Risk Prediction Model for Patients with Generalized Anxiety Disorder Supported by a Multimodal Specialized Disease Database

Construction and Validation of a Novel Depression Risk Prediction Model for Patients with Generalized Anxiety Disorder Supported by a Multimodal Specialized Disease Database

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600119650
Enrollment
Unknown
Registered
2026-03-02
Start date
2026-03-16
Completion date
Unknown
Last updated
2026-03-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Generalized Anxiety Disorder

Interventions

Newly diagnosed depression group (Diagnostically Unstable Recurrence Group):None
GAD group (Diagnostically Stable Recurrence Group):None

Sponsors

Huzhou Third Municipal Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.Meets the diagnostic criteria for Generalized Anxiety Disorder (GAD) according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5); 2.First episode; 3.The Hamilton Anxiety Scale (HAMA) score is >=14, and the 17-item Hamilton Depression Scale (HAMD-17) score is <=14; 4.Han ethnic group, right-handed, aged 18-65; 5.Voluntarily participate and sign a written informed consent form.

Exclusion criteria

Exclusion criteria: 1.Serious suicidal tendencies; 2.History of depression or other mental illnesses in the past; 3.History of drug, alcohol, or other psychoactive substance abuse; 4.Those who do not cooperate with the examination or are unable to complete the examination due to consciousness disorders or visual, hearing, language expression, and comprehension disorders; 5.Individuals with severe physical illnesses (including epilepsy, severe heart, lung, liver, and kidney dysfunction, shock, malignant tumors or hematological diseases, autoimmune diseases); 6.Pregnant or lactating women.

Design outcomes

Primary

MeasureTime frame
Hamilton Depression Scale Score;

Secondary

MeasureTime frame
Hamilton Anxiety Scale Score;

Countries

China

Contacts

Public ContactXiujuan Hong

Huzhou Third Municipal Hospital

xjhong21@126.com+86 572 2290527

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 14, 2026