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Intelligent Intervention Strategies Based on the Synergistic Integration of Large Language Models and Knowledge Graphs

Intelligent Intervention Strategies Based on the Synergistic Integration of Large Language Models and Knowledge Graphs

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600119643
Enrollment
Unknown
Registered
2026-03-02
Start date
2026-03-15
Completion date
Unknown
Last updated
2026-03-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression, Anxiety Disorders, Attention-Deficit/Hyperactivity Disorder (ADHD), and Autism Spectrum Disorder (ASD)

Interventions

Usual care group:Interventions based on clinicians’ treatment plans
Intelligent intervention group:Personalized interventions guided by an intelligent recommendation system

Sponsors

Peking University Sixth Hospital ( Institute of Mental Health )
Lead Sponsor

Eligibility

Sex/Gender
All
Age
6 Years to 18 Years

Inclusion criteria

Inclusion criteria: 1. Age range: 6-18 years old. At 6-12 years of age (childhood), the children's version of the intervention programme usually focuses on behavioural therapy, family intervention and basic cognitive behavioural therapy (CBT). For children aged 6-12 years, there may be more parental involvement because it is more difficult for children at this stage to conduct complex psychological interventions independently. Intervention combining cognitive training and gamification. In the adolescent stage (13-18 years old), adolescents have more mature development in emotion regulation and self-control, so more interventions based on cognitive behavioral therapy can be introduced, especially CBT, mindfulness therapy and self-regulation skills training for anxiety disorders. 2. Diagnostic criteria: meet the DSM-5 diagnostic criteria for depression, anxiety, hyperactivity, or autism. All cases into the group must be through the interview to confirm diagnosis, such as the MINI - KID (MINI International NeuropsychiatricInterview for Children). Psychiatrists with more than 3 years of experience in pediatric psychiatry should conduct the assessment and diagnosis. Staff in each center should be trained centrally before starting the study to ensure the consistency of diagnostic criteria. 3. Comorbidity: Due to the existence of comorbidity between a variety of psychological and behavioral disorders (such as autism often combined with ADHD, anxiety, etc.), subjects were allowed to have comorbidity of other psychological and behavioral disorders, but detailed records were required. 4. Drug treatment: No drug treatment: no drug treatment or drug withdrawal for at least 4 weeks before enrollment (for antidepressants, anti-anxiety drugs, etc.). 5. Stable drug therapy: For children receiving drug therapy, stable drug therapy was required for at least 3 months, with the dose maintained during the study.

Exclusion criteria

Exclusion criteria: Children with a serious physical illness (e.g., cardiovascular disease, severe neurological disease) or psychiatric illness (e.g., schizophrenia) were excluded.

Design outcomes

Primary

MeasureTime frame
Clinical outcome measures;

Countries

China

Contacts

Public ContactHuang Xuebing

Peking University Sixth Hospital ( Institute of Mental Health )

huangxuebing@bjmu.edu.cn+86 10 82805412

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 14, 2026