Adolescent Major Depressive Disorder
Conditions
Interventions
Depression Group:Non-intervention
Sponsors
Affiliated Kangning Hospital of Ningbo University
Eligibility
Sex/Gender
All
Age
12 Years to 18 Years
Inclusion criteria
Inclusion criteria: Patient Group: 1. Age 12-18 years, gender not limited; 2. Meet the diagnostic criteria for depressive disorder episodes in DSM-5; 3. HAMD-17 >= 17; 4. Be capable of completing the scale assessment; 5. The patient and family members signed the informed consent form. Healthy Control Group: 1. Age 12-18 years, gender not limited; 2. In good physical health, with no depression, anxiety, or sleep problems; 3. Be capable of completing the scale assessment; 4. The participant and family members signed the informed consent form.
Exclusion criteria
Exclusion criteria: Patient Exclusion Criteria: 1. Meet the diagnostic criteria for any other DSM-5 psychiatric disorder (comorbid with depression); 2. Have a concomitant severe somatic disease (e.g., epilepsy, cerebral palsy). Healthy Control Group Exclusion Criteria: 1. Other contraindications for magnetic resonance imaging, such as having a pacemaker or metal objects that cannot be removed from the body.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cores of other clinical symptom-related scales;17-item Hamilton Depression Scale (HAMD-17); | — |
Secondary
| Measure | Time frame |
|---|---|
| Neuropsychological measurements related to cognitive behavior;electrophysiological and blood oxygenation indices; | — |
Countries
China
Contacts
Public ContactXiaoli Liu
Affiliated Kangning Hospital of Ningbo University
Outcome results
None listed