Atrial Fibrillation
Conditions
Interventions
PVI + Novel Substrate Modification Group:None
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1.Age >=18 years and =2 years). 3.Willingness to provide written informed consent. 4. Willingness to undergo the procedure and postoperative follow-up.
Exclusion criteria
Exclusion criteria: 1.Prior history of catheter ablation for atrial fibrillation. 2. Planned or prior left atrial appendage closure during the same period. 3. History of cardiac surgery or thoracotomy within the past 3 months. 4. Thrombocytopenia (platelet count 50 mm (measured by two-dimensional echocardiography in the parasternal long-axis view). 7. Presence of left atrial thrombus (confirmed by transesophageal echocardiography or multi-detector computed tomography). 8. Concomitant severe structural heart disease, including: severe mitral regurgitation; clinically significant valvular heart disease; congenital heart disease. 9. Autoimmune diseases (e.g., systemic lupus erythematosus, scleroderma). 10. Active malignancy. 11. Systemic active infection (deemed unsuitable for interventional therapy by the investigator). 12. Pregnancy. 13. Life expectancy <12 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Surgical success rate at 12 months post-operation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Immediate procedural ablation success rate; | — |
Countries
China
Contacts
Public ContactKaijun Cui
West China Hospital, Sichuan University
Outcome results
None listed