Postoperative Delirium
Conditions
Interventions
Group I (nerve block+spinal anesthesia+dexmedetomidine nasal spray group):1.Dexmedetomidine nasal spray: Thirty minutes before surgery, dexmedetomidine nasal spray was administered at a dose of 90 µg,
Group ?(nerve block+spinal anesthesia group):1.Normal saline nasal spray was administered 30 minutes before surgery, using the same method as the first group.
2.The procedures, medications, and doses
Group ? (dexmedetomidine nasal spray+spinal anesthesia group):1.Dexmedetomidine nasal spray: The same as the first group.
2.Spinal anesthesia: The same as the first group
no nerve block was performed.
Sponsors
Yijishan Hospital Affiliated to Wannan Medical College
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >= 65 years; 2. Patients undergoing lower limb hip surgery requiring surgical intervention, with anesthesia administered via subarachnoid block; 3. American Society of Anesthesiologists (ASA) physical status classification I-III; 4. Body Mass Index (BMI): 19.1 - 28.5 kg/m^2; 5. Provided written informed consent.
Exclusion criteria
Exclusion criteria: 1. Allergy or intolerance to a-2 agonists; 2. Severe hepatic or renal dysfunction; 3. Preexisting cognitive impairment or psychiatric disorders; 4. Recent use of other sedative medications; 5. Poorly controlled preoperative cardiovascular disease or diabetes mellitus; 6. Emergency surgery requiring immediate life-saving intervention.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of Postoperative Delirium;Delirium duration; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative PSQI score of sleep quality;Quality of postoperative recovery;Postoperative pain score;Postoperative sedation score;Patient satisfaction;Length of stay and ICU stay;Intraoperative complications; | — |
Countries
China
Contacts
Public ContactChen Yongquan
Yijishan Hospital Affiliated to Wannan Medical College
Outcome results
None listed