major depressive disorder
Conditions
Interventions
Severe Depression Group:None
Healthy control group:None
Sponsors
Shandong Mental Health Center
Eligibility
Sex/Gender
All
Age
18 Years to 30 Years
Inclusion criteria
Inclusion criteria: 1. Inclusion criteria for the depression patient group: (1) Physically healthy; (2) Meet the DSM-5 clinical diagnostic criteria for depressive disorder and are in the clinical depressive phase; (3) Agree to undergo MRI scanning; (4) Aged 18-30 years; (5) Willing to participate in this study and sign the informed consent form; 2. Inclusion criteria for the healthy control group: (1) Physically healthy, with no current diagnosis of psychiatric disorders; (2) Agree to undergo MRI scanning; (3) Adolescents aged 18-30 years; (4) Willing to participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Exclusion criteria for the patient group: (1) Bipolar disorder, psychotic disorders; (2) Current substance dependence; (3) Severe neurological diseases (e.g., epilepsy); (4) Unstable physical illnesses; (5) Contraindications to MRI (e.g., metal implants, pacemakers); (6) Pregnancy (if MRI is not allowed); 2. Exclusion criteria for the control group: Same as the exclusion criteria for the patient group.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Magnetic Resonance Imaging;Electroencephalogram;Beck Depression Inventory-II Score;Patient Health Questionnaire-9 items;Hamilton Depression Scale Score;Speed and Valence in Word Association Tasks;Reaction Time and Accuracy in Dual-Task Paradigms; | — |
Countries
China
Contacts
Public ContactYunshao Zheng
Shandong Mental Health Center
Outcome results
None listed