Vertical alveolar ridge defect in the posterior region
Conditions
Interventions
Experimental group:Bone grafting using a mixture of recombinant human bone morphogenetic protein-2 (rhBMP-2) and bone substitute material.
Sponsors
Beijing Stomatological Hospital , Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1.Diagnosed with partial edentulism, with the missing-tooth area in the posterior region, and planned for fixed prosthetic rehabilitation; 2.Moderate-to-severe vertical bone defect, with vertical bone resorption = 4 mm; 3.Aged 18–60 years, any sex;
Exclusion criteria
Exclusion criteria: 1.Moderate-to-severe horizontal bone defect; 2.Acute or chronic inflammation in the edentulous area; 3.Pregnant or lactating women; 4.Individuals with psychiatric disorders or intellectual disabilities. 5.Uncontrolled systemic diseases, such as uncontrolled diabetes mellitus, myocardial infarction within the past 6 months, congestive heart failure, or severe coagulation disorders; 6.Severe immunocompromise, such as uncontrolled HIV/AIDS or long-term high-dose immunosuppressive therapy; 7.Bone metabolic disorders, such as osteoporosis;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bone augmentation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Complications; | — |
Countries
China
Contacts
Public ContactJiabao Zheng
Beijing Stomatological Hospital , Capital Medical University
Outcome results
None listed